Tilly's Fanconi Test Results

[Quercus]

@agilebasenji:

Didn't one of the Jones dogs have Fanconi that was spilling sugar but never had symptoms due to the diet being fed? Seems like I read that years ago in the Basenji mag or the BCOA. (But please don't get too excited based on my questionable memory.)

They attributed it to the diet…but nobody really knows. This was before the test, but there was some talk that some "carriers" may spill a little sugar, but never have significant metabolic changes.

There have been some lines of Bs that have NEVER had any dogs spill sugar, that are having some dogs test as carriers and affecteds. The pattern of inheritance with these lines is true, so it doesn't seem to be a problem with the test, but more of something that these dogs have some sort of modifier (Lisa can probably word this better) that supresses the expression of the Fanconi.

[Quercus]

I am sorry, Scott. But hopefully you won't ever have to deal with the Fanconi symptoms, or if you do it will be a long time from now.

[Janneke]

Sorry to hear this, but always better to know so you can be prepared.

Good luck at the show

[MacPack]

Yes, better to know. You can urine strip test weekly instead of monthly so you get the earliest possible head start on the protocol. And it is "probable" affected after all.good luck that you have her for many years!

[moetmum]

I am so sorry to hear your test has come back prob affected, your girl is not the first prob aff by the sire, so he must be at least a carrier. I wish more would test. At least you are now aware and can watch out for it, there is a good support system on this forum with experience of this condition, I hope you don't need to use it for many many years.

[Tiva]

Sorry to hear about this.

your girl is not the first prob aff by the sire, so he must be at least a carrier

He is not tested, but he is a carrier. He had 3 litters in UK (with 2 females), all before test was available. Unfortunately, one Dam was latter tested AFS (one of pups too, but some pups are carriers, so Sire can't be AFS) and Tilly's Mum is obviously at least a carrier.

[basi]

@Tiva:

Sorry to hear about this.

He is not tested, but he is a carrier. He had 3 litters in UK (with 2 females), all before test was available. Unfortunately, one Dam was latter tested AFS (one of pups too, but some pups are carriers, so Sire can't be AFS) and Tilly's Mum is obviously at least a carrier.

All the more reason that the owner/breeder of the dam should have tested her before using him:rolleyes:

[Tiva]

Yes, I agree. And if dam is clear, her owner can use Ruben for breeding.;)

[BasenjiDiva]

I am so sorry. She is so young and who knows what treatment advances are coming up in the near future!

Pat

[wizard]

So sorry to hear this - but a heads up is better than a surprise later on.

[dmcarty]

I believe that many have had great success with the Gonto's Diet - the Jones girls were feeding raw I believe. I see not reason why you could not do the Gonto's diet - obviously with out the blood gases etc. But the Red meat long grain protein and pet tab plus and 1 x month amino fuel along with a tbls of meat type canned food. Can't hurt and might help.

[MarleyJo]

I am so sorry. Hopefully all will go well. Many of us have been through this and it seems every case is different. We were lucky with our girl Marley. Just a couple of pills twice a day and you would never know. She had a long happy life. Fingers crossed and best wishes.

[Elscodobermann]

Thanks everyone. All of your comments have made us feel more positive about Tilly's future - also at WELKS today we were overwhelmed by all the people who came over to speak to us about it - i suppose as they say bad news travels fast - but everyone was very positive about it i.e its not the end of the world, and pleased that she had been tested - i am just astounded that testing your dog over here is not a matter of course…..

Tilly only got 2nd in postgrad today - she should have won! Anyway, really enjoyed the show, and have spoken to a lot of people with years more experience than us in Basenjis who have given us so much encouragement and advice.

As for Tilly - we got home at 9pm, my mum had left a lovely roaring log fire on for us - Tilly promptly chased all the dobes away from the fire and settled down in the prime spot nearest the heat - she knows shes special! Meanwhile me n john have just poured a little of the "amber nectar" to celebrate a very enjoyable weekend - basenji people aint all that bad.

[basi]

@Elscodobermann:

Thanks everyone. All of your comments have made us feel more positive about Tilly's future - also at WELKS today we were overwhelmed by all the people who came over to speak to us about it - i suppose as they say bad news travels fast - but everyone was very positive about it i.e its not the end of the world, and pleased that she had been tested - i am just astounded that testing your dog over here is not a matter of course…..

Tilly only got 2nd in postgrad today - she should have won! Anyway, really enjoyed the show, and have spoken to a lot of people with years more experience than us in Basenjis who have given us so much encouragement and advice.

As for Tilly - we got home at 9pm, my mum had left a lovely roaring log fire on for us - Tilly promptly chased all the dobes away from the fire and settled down in the prime spot nearest the heat - she knows shes special! Meanwhile me n john have just poured a little of the "amber nectar" to celebrate a very enjoyable weekend - basenji people aint all that bad.

Glad you enjoyed your day:D How nice to come home to a ready made fire:D

I wish also that more people would test but hey ho! I'm not familiar with the bitch that won your class was she a brindle? I see Tilly's full sister had a good day winning BOB.

[Elscodobermann]

hi Basi - the bitch who won the class was a red - but she was withdrawn from the challenge for some reason.

[basi]

@Elscodobermann:

hi Basi - the bitch who won the class was a red - but she was withdrawn from the challenge for some reason.

Hmm wonder what happened there then

[Patty]

Just read about your results and would join the others in saying how sorry I am.

Personally I do not agree with carriers being used as they will only produce more carriers!
The argument is used that good breed points will be lost but they are often lost any way - no guarantee that they will be passed on! 'Ss' law says they won't!

Tilly is a lovely bitch - yes you were right about the results at WELKS she should have been 1st in her class. I will be very interested to read the judge's critique. The bitch was withdrawn because she had been frightened.

Best wishes for future successes.

[Quercus]

@Patty:

Just read about your results and would join the others in saying how sorry I am.

Personally I do not agree with carriers being used as they will only produce more carriers!
The argument is used that good breed points will be lost but they are often lost any way - no guarantee that they will be passed on! 'Ss' law says they won't!

Tilly is a lovely bitch - yes you were right about the results at WELKS she should have been 1st in her class. I will be very interested to read the judge's critique. The bitch was withdrawn because she had been frightened.

Best wishes for future successes.

A carrier bred to a clear will produce carriers AND clears…you could keep a clear and be done with carriers (by having them spayed or neutered) in one generation.

I can respect that you wouldn't want to use a carrier...but there is nothing wrong with breeders who do.

[lvoss]

Everytime we choose not to use a dog diversity is lost in our genepool. We lose so much already due to things like popular sire syndrome it would IMO be catastrophic to the breed to further reduce diversity by eliminating all carriers simply because they are carriers. There are far more issues in the breed than just Fanconi and all bottlenecking for one reason or another will only help to express other issues in the breed like a rise in PRA, HD, Hypothyroidism, or some other condition that may currently be quite rare. It is better for the breed that the gene is eliminated over several generations.

[dcmclcm4]

Even though I am not a breeder, I totally agree with using carriers and even male affecteds bred to a clear. I rescue Bs and have had only a few affecteds but I have quite a few with different eye diseases, probably all of them genetic. I worry about the other diseases that will occur more frequently when one limits the breeding diversity!

As long as the breeder keeps track of the carriers and do not allow them to breed to another carrier and/or affected then I see no problem. I do know accidents and things happen though.

Owning and taking care of an affected is not the worst thing that could happen. I own one and she is doing great at 10 1/2.