eeeefarm You wrote: My other question…...subject of another thread perhaps......is whether we can definitely say we should not breed from Fanconi affected. Are there other, desirable, traits associated with and perhaps genetically intertwined with Fanconi that are worth preserving? Is there something environmental at play that determines the expression of the gene, and if we can identify that environmental factor would it be possible to suppress Fanconi by avoiding it? These questions are seldom black & white, and the science is still quite new. We could be guilty of "throwing the baby out with the bathwater" if we are not careful. Inherited genes often give some sort of advantage that may not be immediately apparent.......which may be why they continue to be passed on. (e.g. humans with heterozygous sickle cell anemia genes have resistance to malaria).
I fully believe that there is nothing wrong with breeding a Clear to an Affected male, depending on if this particular male might be the end of some bloodlines and a way to carry them on if this is a dog that really has something to offer the breed that we don't want to lose. I do not nor would I ever breed an affected or tested affected bitch. This is a question that each breeder must answer for themselves. There IMO, is no right or wrong. And by not having this consideration, you are throwing the baby out with the bath water.... and I believe that happened when the HA recessive gene was found and affected and carriers were culled from breeding programs.