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Fanconi Testing

Basenji Health Issues & Questions
  • One thing to keep in mind when looking at these numbers and other statistics, dogs that are already clinically affected are probably under represented because people already know their status. So though there are only 6% Probably Affected of the ones that have been tested people with known affecteds may not be submitting samples.

    Another thing to add, if you have a known affected your dog's blood can help the researchers to find the direct gene test for Fanconi. Please check out the FAQ, http://www.basenjihealth.org/linkage-faq.html, and read about their call for clinically diagnosed affected dogs. These dogs will have their samples run for free and will help the entire breed by allowing researchers to locate the actual gene that causes Fanconi Syndrome.

  • @lvoss:

    One thing to keep in mind when looking at these numbers and other statistics, dogs that are already clinically affected are probably under represented because people already know their status. So though there are only 6% Probably Affected of the ones that have been tested people with known affecteds may not be submitting samples.

    Another thing to add, if you have a known affected your dog's blood can help the researchers to find the direct gene test for Fanconi. Please check out the FAQ, http://www.basenjihealth.org/linkage-faq.html, and read about their call for clinically diagnosed affected dogs. These dogs will have their samples run for free and will help the entire breed by allowing researchers to locate the actual gene that causes Fanconi Syndrome.

    Thanks for posted that.. and glad that you brought that up about the affected… and also, many of the affecteds were used during the deveopment of the test....

    One note about the "call" for clinically affected, only the test is free, you have to pay your Vet to have the blood drawn and sent.....

  • If you have an affected and want to send sample you can also look for an upcoming blood draw clinic in your area. The 2007 Nationals will be having a blood draw clinic.

  • I think when breeding season is over all the pet folks should have their dogs tested.
    The results will tell you what you will be dealing with in the future.
    Knowledge is power.
    We all need to know how our dogs health is.

  • I think it is important for pet owners to contact their dog's breeder and ask if the parents have been tested. If one parent has tested clear then the worst the dog can be is a carrier and will not become ill. If there is no clear parent then the dog will need to be tested or if the parents are not tested then the dog should be tested.

  • @lvoss:

    I think it is important for pet owners to contact their dog's breeder and ask if the parents have been tested. If one parent has tested clear then the worst the dog can be is a carrier and will not become ill. If there is no clear parent then the dog will need to be tested or if the parents are not tested then the dog should be tested.

    Exactly… of course for the many rescues that don't know the breeding or for 99.9% of the pups that came from BYB or Pet stores, I think we can all agree the parents were not and will not be tested....

    And really they are doing all "comers" now, not just breeding dogs...

  • This week's update is in and the new numbers look something like this

    53% or 188 Basenjis - Clear/Norman
    5% of 18 Basenjis - indetermint (between a clear and a carriers)
    35% or 122 Basenjis - Carrier of the Fanconi Gene
    7% or 24 Basenjis - Affected with Fanconi

  • @lvoss:

    This week's update is in and the new numbers look something like this

    53% or 188 Basenjis - Clear/Norman
    5% of 18 Basenjis - indetermint (between a clear and a carriers)
    35% or 122 Basenjis - Carrier of the Fanconi Gene
    7% or 24 Basenjis - Affected with Fanconi

    And a note on the indetermints, one that was listed this way has produced a Basenji with that is showing affected with the gene test, so that would indicated that his status would now be a carrier

    Again, as Lisa noted before, this is not a ture number for affected since many that are now showing expression are not being tested or have been used in the development, also not being shown

  • re: puppy mills and testing only one parent - I know for a FACT that at one place the sire of several years of litters was not the sire - it was a male who had good papers so his name was listed even though he was DEAD. One of the PM's males was the sire of several litters attributed to this OTHER dog. (I happen to know the person who owned the substitute sire)

    So it is unfortunate but the testing will only be as ethical as those who provide information to the test.

    Geez I hate to even say that but I am afraid that it's true.

  • @dmcarty:

    re: puppy mills and testing only one parent - I know for a FACT that at one place the sire of several years of litters was not the sire - it was a male who had good papers so his name was listed even though he was DEAD. One of the PM's males was the sire of several litters attributed to this OTHER dog. (I happen to know the person who owned the substitute sire)

    So it is unfortunate but the testing will only be as ethical as those who provide information to the test.

    Geez I hate to even say that but I am afraid that it's true.

    No doubt about that… and another reason to only look at AKC who has a DNA parentage program for high volume breeders...

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