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Fanconi Disease

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  • Cushings Disease

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    D
    Here is the test information that Missy had done and an article with the portion that includes Melatonin for treatment. I have inlcuded the webpage for the entire article. She has not been on the Melatonin long and I am slowly increasing her dosage but she is definitely not as puffy in the intestinal area as she was. The Adrenal Panel with Combined Dex Supp/ACTH Stim Test for Dogs: The following hormones are tested in the adrenal panel: Cortisol, Estradiol, Androstenedione, 17-Hydroxyprogesterone, Progesterone and Aldosterone. REVIEW ARTICLES Steroid Profiles in the Diagnosis of Canine Adrenal Disorders Jack W. Oliver, Proceedings 25th ACVIM Forum, Pp. 471-473, Seattle, WA. 2007. http://www.vet.utk.edu/diagnostic/endocrinology/pdf/Steroids%20Profiles%20in%20the%20Diagnosis%20of%20.doc Melatonin. Results of in vitro cell culture (human H295R adrenocortical carcinoma cells) studies in our lab55 revealed that both 21-hydroxylase and aromatase enzymes were inhibited by melatonin. Also, in dogs with adrenal disease that are treated with melatonin, and repeat adrenal steroid panels are done, cortisol levels are consistently reduced, and estradiol levels are variably reduced.29 Inhibition of the 21-hydroxylase enzyme would lower cortisol levels, and inhibition of the aromatase enzyme would lower estradiol levels. Estradiol levels were decreased in a prior study of dogs treated with melatonin.31 Results of in vitro studies with human MCF-7 breast cancer cells also revealed that melatonin inhibited aromatase enzyme, which resulted in reduced estradiol levels.56 Melatonin treatment for cases of mild adrenal disease in dogs may be effective, and particularly in cases where sex steroids are increased. Jennifer
  • Fanconi Testing

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    tanzaT
    The more data that is in the data base, the better people can use the that information as this is a Linkage test only… and errors can be made either human or test....
  • No Fanconi at Sherwood!

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    P
    my boy is finiggy! he wont eat his dog food, he's sooo darn picky! i get a bag and he'll eat it for a week and then stop all together! for no reason!. anyone have any idea's on how i can get him to eat his DOG FOOD!, NOT PEOPLE FOOD!!. HE DIDN'T EAT FOR 3 DDAYS ONE TIME!. talk about being stubborn!!!!>
  • Fanconi Results

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    BenkuraB
    That's great news. I bet you're glad the waiting is over. :)
  • Fanconi Question

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    E
    Thank you for all the information. I am going to a dog show in Springfield, Illinois next weekend to meet some dogs from Meiterhaus (Tad Brooks). This makes me feel alot more comfortable. :D
  • Question About Fanconi

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