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Question About Fanconi

Basenji Health Issues & Questions

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yag113
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Hi…I have a 9 year old Basenji with slightly elevated liver enzymes. I am familiar with Fanconi syndrome as a kidney disorder. I had the dog to the vet and he ran tests for Cushings. That was ruled out. We did blood work...the only thing outside of normal range were liver enzymes.. ALKP / 463 U/L and ALT 259 U/L. She is drinking a bit more than usual but well within the accepted normal range of 1 oz. per pound of body weight. We also did a hypo thyroid test...a little on the high side but within normal range. I had a dog with Fanconi but liver enzymes were never an issue. Does anyone have any thoughts on this situation? Could this be an early warning sign of Fanconi? I would appreciate any and all help!
Thanks
Gay F.
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• • • DebraDownSouth

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@JoT:

Salis,
Please contact Liz Hansen at the research lab and inform her of this situation. She will need the full names of your dog and both parents. Please send her an email at : HansenL@missouri.edu,

Liz is very nice and quite helpful. She will help you understand the results. She will investigate your test.

JoT, thank you! I've already wrote Liz Hansen:-)

I'm a bit unlucky with it test, i made order in January and after half a year I got this result! Lucky it's not affected!
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@lukris:

That's good news about Chance Vicky. At least you know you have to find a nice clear boy for Nakura now. You must be relieved.

Chance is Nakura's son so can't use him! The search continues. We need to encourage more people to test are there are only about 6 clear stud dogs in UK at moment. So not much too choose from there!!
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• • • seko

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It is coming back through your e-mail, as long as you are the one who registered your dog with the CPP site.

For me the blood left europe june 23rd and I was surprised I got the results so soon, when I open my e-mails I thought the CPP was just telling me they got the blood in, then I think I almost fell out of my chair as the 1st result I saw was an affected, in the process I missed one and was two frightned to open the last one, the clear one was the last one, gave me a bit of rest to go back and notice that probably carrier was not a bad result.

The thing is I didn't expected Thorn to be an affected, Eos I was a bit worried as well as for her and Thorns kids, Timbo and Vahli, a few people are saying her father died of fanconi.

But I don't feel I am alone in this and I am sure of something, it is the last time I will ever get worried about getting a probably affected puppy, thanks to the test and people who made it happen.
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• • • Terry

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@Terry:

I heard a rumor, wondered if anyone knows if it's true. The rumor was that an affected dog has been identified with 2 clear parents.

Pat, I know you're usually up on this…

Terry

That seems to be the case, Lisa will most likely also chime in. They are now retest that dog along with his parents. As we all know there is always human error and the samples may have been mismarked. I have no doubt in the test (and I know that others will mostly likely use this as a way to discount the test), but I will stand on the over 1100 samples that have already been done and they all seem to be as they should. IMO and I have a sample that was most likely taken at the same time, that there was either a problem when the sample was sent in or there was a problem when the DNA was extracted. At the same time and the sample taken at the same time, there is another dog that is showing as Carrier from two clears… again that is being retested also...
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• • • erpeden

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Thank you for all the information. I am going to a dog show in Springfield, Illinois next weekend to meet some dogs from Meiterhaus (Tad Brooks). This makes me feel alot more comfortable. 😃
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• • • tanza

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@dmcarty:

re: puppy mills and testing only one parent - I know for a FACT that at one place the sire of several years of litters was not the sire - it was a male who had good papers so his name was listed even though he was DEAD. One of the PM's males was the sire of several litters attributed to this OTHER dog. (I happen to know the person who owned the substitute sire)

So it is unfortunate but the testing will only be as ethical as those who provide information to the test.

Geez I hate to even say that but I am afraid that it's true.

No doubt about that… and another reason to only look at AKC who has a DNA parentage program for high volume breeders...

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Question About Fanconi

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