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What exactly is PK Deficiency?
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How common is it? I have never heard anyone mention it over here in the UK before.
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It is not very commonly found ever since testing has been available for it. It is recommended that if you are just starting out and do not know the testing history of your dog's pedigree to test because there are still carriers in the population though fairly uncommon now. It can be done via cheek swab DNA test.
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I think I got the same enquiry. I answered along the lines lvoss has described. (Bryn was DNA tested for this when he was still in the US).
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Hmmm think I also got the same one.
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So, is this another test we should do on the same lines as fanconi?
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So, is this another test we should do on the same lines as fanconi?
I shall be checking this out with my breeder! I suspect that she may have had the same enquiry herself. However, we do know the lines our dogs have come from and I would think that there is nothing to worry about.
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This is a recessive gene, like Fanconi. It can stay "hidden" for years worth of breeding. Like Fanconi, if you don't test, you don't know. Since this is a direct gene test, most of us consider if the sire and dam are clear the pups are also clear. But as Lisa said, there are still lines out there being bred that are not tested and that carry the gene.
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OK, so can we get the test done in the UK by our own vet, or do we need to go down the same route as the fanconi testing?
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There is a lab in the UK on the OFA website but I didn't see PKD on their list of tests though you could contact them to find out.
HealthGene and VetGen definately do offer the test.
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OK, so can we get the test done in the UK, or do we need to go down the same route as the fanconi testing?
I know that Chris sent Cali's parents tests to VetGen for the test so not sure if there is anywhere in the UK for it
Belle's parents were tested in Germany so they can do it there. -
I've just checked Vet Gen and they do test. Not entirely convinced if it is necessary though. There is some info in Elspet Ford's The Complete Basenji, Also known as Haemolytic Anaemia. She says the condition was prevalent in the sixties but that the disease has declined until at present time it is virtually unknown due to selected breeding/exclusion of carriers. Does anyone know of any recent cases? would be interesting to find out.
Theresa
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Here is a carrier in the OFA database. Unlike the Fanconi test, I don't think owners have to submit their results to OFA in order to recieve results for their tests.
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I've just checked Vet Gen and they do test. Not entirely convinced if it is necessary though. There is some info in Elspet Ford's The Complete Basenji, Also known as Haemolytic Anaemia. She says the condition was prevalent in the sixties but that the disease has declined until at present time it is virtually unknown due to selected breeding/exclusion of carriers. Does anyone know of any recent cases? would be interesting to find out.
Theresa
This is not like the Fanconi test where the results are open and published. People had to submit the test to be posted on OFA, so there is no way really to know the status of a dog/bitch unless tested. Again, as with all testing, if you don't test, you don't know.. and while I believe it is pretty rare these days, I certainly would be testing if I didn't know what the background of the dogs in the pedigree were…. but that is just me.... remember Carrier genes can hide for generations... just look at the Fanconi results... entire kennels came back as carriers, yet the breeder said they didn't have one with Fanconi ever... playing the odds .... and till the test came out they really would not have cause to think otherwise... but in another two years and the entire breeding program would have imploded.
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Have many of the forum members had their Basenjis tested for PK?
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I have and mine are listed on the OFA site… but I only test the ones that I was breeding and since the sire's and dam's were clear, I didn't feel the need to test the off spring. Note too, if you search the OFA data base there is not many in there at all.. not like Fanconi were the results are automatically published.
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I've seen the odd one or two, but there doesn't seem to be many.
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For those here, like me, who has no idea what this is…......
https://www.vetconnect.com.au/5min/data/10061006.htm
Thank you for this topic. Learn something new every day
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Thanks for that link snorky998 and thanks to everyone else that has replied too.
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I've seen the odd one or two, but there doesn't seem to be many.
My point exactly.. since it is not a required test that is listed on OFA site.. and it is the person option to send in the results… not many did... so unless they have tested and have the results (paper in hand) you don't know...
Think about it.. in 20 yrs will people still be sure to make sure that testing was done for Fanconi?... same as HA/PK testing... just because we have not seen it, doesn't mean it is not out there
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Yep I have had my 2 tested, and Vanda will be tested when she is a little older. I will be putting the results upon the OFA site, as soon as I build up my dog account :)… As I am only starting out in the breed, I want my dogs to be tested for all of whats available. I have been so badly burned by people with the ACD's, that I made the decision that I will be doing all the availale testing with the B's... Its been told t me, that in Aus there would be very little chance of HA affected dogs, but, at the same time, hardly anyone is testing their dogs, so as Tanza says, how do we know, if there is no testing being done ???
While reading through this thread I was thinking about us B breeders, talking about Fanconi, the same way we are talking about HA now... Wouldnt it be great to think that there may only be a few dogs world wide, that were only carriers of Fanconi :), No more affected dogs, only a few Carriers, and the greater majority of dogs being clear........SIGH........
