First, a nod to eeeefarm. Sometimes over the last 9 years I have called Pam to tell her an issue I'm having suddenly with Cara and most times her response is "I don't know. What's upsetting you?" And she's right. She feeds on my feelings.
I am sorry for what you are going through, and hope you find the right balance. I have never had a dog with generalized separation anxiety. We had a rescue poodle that fixated on Leora for about 6 mos but got over it once he realized she left and came back every time.
The super crates that can prevent escape or injury are sometimes necessary, especially if the dog is likely to hurt itself or risk damage while demolishing the house. In times when crating is critical, they can buy you time to sort out the problem.
One thing I didn't notice anyone suggest is a thundershirt. I laughed at them, then began researching, bought ones for Cara and Arwen. They really can help some dogs.
Not separation related, but still anxiety...Cara used to worry about rain to the level of obsession, refusing food or water, holding her bowels til they exploded. We put her on prozac and a lot of her fearful behaviors subsided. I don't recommend any drug long term for a situational problem. We are working on scaling Cara's dosage back, but at some point, quality of life counts.
If Prozac stopped working, I would certainly try cbd with research/vet guided dosage. It's something only the owner can decide on.
Tested on animals, including dogs, given internally. Yes, research has been delayed due to archaic laws but fortunately, there are studies and many more coming.
As for experience, 1 basenji vs around one hundred basenjis.. hmmm. I don't always agree with Pam, but I darn sure always ask for her input.
But, read for yourself if you believed not for ingestion and no testing on domesticated animals. <eye roll>
. https://www.avma.org/News/JAVMANews/Pages/180801a.aspx <--- why the delay and early research on dogs
https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476 <--- fda approved for children, push for vet use of animals with seizures
Dr. Joe Wakshlag of Cornell University’s College of Veterinary Medicine tested CBD oil to see if it could help dogs who are experiencing pain from osteoarthritis. His results were "significant, according to the researchers with over 80% of the dogs taking the CBD oil showing “significant improvement in pain levels and quality of life” without discernible side-effects."