The easiest for me was an upside down dog on my lap, pointed away from me to give me good access to the toes. I used a guillotine clipper and was careful not to take too much, finished up with a file or emery board to be sure of not nipping the quick. Of course they don't like it, but should learn to tolerate it as with any other procedure (ears, anals, teeth). Start off easy, lots of praise for good behaviour, many breaks. Once the dog is familiar with the procedure you should be able to manage with a short break when the dog gets restless, perhaps a treat, but leaving is not allowed without permission. (my girl Tamu used to get increasingly annoyed as I worked, inform me verbally she was not amused, and make a slow motion mouth grab of my offending hand. Never bit down but gave me that look Basenjis use when you are out of favour, and I would allow her a minute to compose herself before continuing the "torture". The hardest part, for me, was not to laugh!)
Most breeders will have spent some time with pups getting them used to being handled. Once they come home with you it's important to continue touching anywhere and everywhere, examining whatever part of their anatomy you wish. You do not want any "no go" zones! In case of injury or illness it's important they are used to being handled everywhere.