When I brought my pup Liyah home at 11wks, I had a 3 hr drive home. She wimpered for the first 15 minutes and then slept for most of the rest of the ride. When she did briefly wake up she didn't make a peep. I never stopped to let her out on the drive home - her breeder had recommended against it, even if she made a mess.
I will say that in my case I visited her every week after she was born so she already knew me. That said, even though she knew me, she was suddenly away from her brothers and sisters - so I'm sure that was why she wimpered in her crate. Be sure to have the breeder give you one of the toys your pup played with at their house - Liyah still has hers in her crate 15 months later.
Oh, one last thing. Liyah's breeder had already started the crate training before I took her home. I think that is pretty normal with responsible breeders.