That's what I'm wondering also - is she sensing hormone changes? Geez, you think after 7 years you know a dog but she is acting totally differently! I really hope we can figure something out - it makes me sad to see her so anxious and not at ease, and I'm tired of cleaning up pee! I have a high tolerance for pee cleanup since she has Fanconi, but 5 times in one day is just ridiculous.
Oh and, I spray/wipe down the area she peed with a vinegar/water solution…..