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Fanconi DNA Test

Basenji Health Issues & Questions

5/21

23 Feb 2008, 23:25

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    I sent a message to the Fanconigroup today stating this and asked what the procedure was for joining the group. Jennifer
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    Ooops - But I do think it would be fun to get the results. Thanks Nicola for doing this thread - It's quite interesting.
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    @wizard: I've looked at that website but still don't understand the reason behind doing this test. It doesn't check for genetic defects just parentage. It seems it undeniably verifies parentage, but isn't that what the AKC registration does? There must be something I'm missing. It is to prove parentage… as you could put any name of any dog on a set of papers and sent them it.... which in cases of Puppy Millers and some BYB's that is was was being done..... so the parents were NOT the parents of a given puppy. If you read the minutes each month on the AKC site (Secretary's page) you can see how many litter registrations were reversed "due" to DNA parentage.
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    No the parents were not. Most of her dogs that have been tested have been negative for fanconi so I figure my chances are good that EL D will be fine.
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    @Terry: I heard a rumor, wondered if anyone knows if it's true. The rumor was that an affected dog has been identified with 2 clear parents. Pat, I know you're usually up on this… Terry That seems to be the case, Lisa will most likely also chime in. They are now retest that dog along with his parents. As we all know there is always human error and the samples may have been mismarked. I have no doubt in the test (and I know that others will mostly likely use this as a way to discount the test), but I will stand on the over 1100 samples that have already been done and they all seem to be as they should. IMO and I have a sample that was most likely taken at the same time, that there was either a problem when the sample was sent in or there was a problem when the DNA was extracted. At the same time and the sample taken at the same time, there is another dog that is showing as Carrier from two clears… again that is being retested also...
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    @dmcarty: re: puppy mills and testing only one parent - I know for a FACT that at one place the sire of several years of litters was not the sire - it was a male who had good papers so his name was listed even though he was DEAD. One of the PM's males was the sire of several litters attributed to this OTHER dog. (I happen to know the person who owned the substitute sire) So it is unfortunate but the testing will only be as ethical as those who provide information to the test. Geez I hate to even say that but I am afraid that it's true. No doubt about that… and another reason to only look at AKC who has a DNA parentage program for high volume breeders...