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Fanconi Testing Question

Basenji Health Issues & Questions

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3 Sept 2007, 03:44

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    We hope the results are good, and we will cheer if they are, and if they aren't, we will support you. Do let us know what you have found please.
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    No the parents were not. Most of her dogs that have been tested have been negative for fanconi so I figure my chances are good that EL D will be fine.
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    @etzbseder: Thanks, I've seen that before, but forgot about it. After looking at that, it shows that my answer would be: Clear pups ONLY means that neither parent is affected, and that does not change with multiple clear pups. The only thing that shows any determination of the parents is a test of the parent themselves (or if their grandparents are clear). correct. The more clear pups (with no affecteds or carriers) you had from the breeding of the same two animals, the more LIKELY it is that the parents are clear…but it certainly would not be a for sure.
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    @Mia: I don't know who her grandparents are, how would I find that out (website)? I have the registration #'s for both her parents. You can order a pedigree from AKC, www.akc.org and then go to the store link. You can order it on line as an electronic file for 10.00. Most breeders give you an extended pedigree?
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    @Terry: I heard a rumor, wondered if anyone knows if it's true. The rumor was that an affected dog has been identified with 2 clear parents. Pat, I know you're usually up on this… Terry That seems to be the case, Lisa will most likely also chime in. They are now retest that dog along with his parents. As we all know there is always human error and the samples may have been mismarked. I have no doubt in the test (and I know that others will mostly likely use this as a way to discount the test), but I will stand on the over 1100 samples that have already been done and they all seem to be as they should. IMO and I have a sample that was most likely taken at the same time, that there was either a problem when the sample was sent in or there was a problem when the DNA was extracted. At the same time and the sample taken at the same time, there is another dog that is showing as Carrier from two clears… again that is being retested also...
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    @dmcarty: re: puppy mills and testing only one parent - I know for a FACT that at one place the sire of several years of litters was not the sire - it was a male who had good papers so his name was listed even though he was DEAD. One of the PM's males was the sire of several litters attributed to this OTHER dog. (I happen to know the person who owned the substitute sire) So it is unfortunate but the testing will only be as ethical as those who provide information to the test. Geez I hate to even say that but I am afraid that it's true. No doubt about that… and another reason to only look at AKC who has a DNA parentage program for high volume breeders...