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Major behavior change after 10 years!! Help!

Behavioral Issues
  • DebraDownSouthD

    @rocky1 ...as i
    I wrote in 2016...I am sorry about your dog, but it's rare. Other drugs may be more dangerous and far less researched.

    DebraDownSouth Aug 28, 2016, 11:18 PM reply quote
    Rocky1, I am sorry about your dog, and absolutely liver is a KNOWN side effect, albeit small, with the drug. So anyone doubting you needs to do some research.

    However, your other information is a not accurate.

    first, no, clomicalm is not the doggy form of prozac.

    Second, 5-htp has toxicity also. Almost no drug comes without risks. http://www.ncbi.nlm.nih.gov/pubmed/10863592
    Add to the fact that prozac has been used and researched heavily, whereas research on 5-HTP is scarce in humans and almost nonexistent in dogs beyond the toxicity above. "natural" doesn't mean safe.
    http://psychology.wikia.com/wiki/Hydroxytryptophan_(5-)

    In humans it also can cause liver damage

    Tryptophan use has been associated with the development of serious conditions, such as liver and brain toxicity, and with eosinophilic myalgia syndrome (EMS), a potentially fatal disorder that affects the skin, blood, muscles, and organs (see "Overview" section). Such reports prompted the FDA to ban the sale of all tryptophan supplements in 1989. As with tryptophan, EMS has been reported in 10 people taking 5-HTP.
    Side effects of 5-HTP are generally mild and may include nausea, heartburn, gas, feelings of fullness, and rumbling sensations in some people. At high doses, serotonin syndrome, a dangerous condition caused by too much serotonin in the body, could develop. Talk to your health care provider before taking higher-than-recommended doses.
    People with high blood pressure or diabetes should talk to their doctor before taking 5-HTP.
    If you take antidepressants, you should not take 5-HTP (see "Possible Interactions" section).
    People with liver disease, pregnant women, and women who are breastfeeding should not take 5-HTP.<<

    Clomicalm (clomipramine hydrochloride) is a tricyclic antidepressant and affects chemicals in the brain (serotonin)
    Prozac, fluoxetine, is a selective serotonin reuptake inhibitor (SSRI) antidepressant drug . Its FDA-approved veterinary formulation is known as Reconcile.

    Clomicalm slows the reabsorption rate of the neurotransmitters serotonin and norepinephrine, allowing their levels to rise in the brain. This drug is mainly used to treat separation anxiety. Prozac, on the other hand, works by strongly blocking the reabsorption of serotonin allowing more serotonin to be available for extended periods of time.
    http://www.ehow.com/info_12227764_difference-between-clomicalm-prozac-dogs.html

    http://www.ncbi.nlm.nih.gov/pubmed/10863592

    Prozac, clomicalm and 5-HTP can all cause liver issues.

    Debra<<<<<

    Debra

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  • J

    @rocky1 I'm so very sorry for your loss. They become such a part of our souls. I've already had a few tears over just the thought of what it will be like without him.

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  • B

    Help please!

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    D
    @basenji_life said in Help please!: Oh and yesterday evening she started peeing on the sofa while looking straight at him... and she normally goes outside to pee... maybe she was upset that he was home? Did you solve this issue? I had a dog who didnt like kids. Someone told me it could be because the previous owner had kids who scared the dog. So it could be a traumatic experience for the dog. And when kids were around, the dog would bark a lot always.
  • wizardW

    Change in travelling behavior

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    wizardW
    It started several months before the second dog arrived. Maybe the lack of visibility is the issue - I raised the platform yesterday so the kennel sits a little higher (though maybe not high enough) so we'll see tonight (of course it will be dark out and cold so probably not a good test).
  • Chealsie508C

    Teenage years

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    svdreamerS
    I guess we did primative puzzle challenges with Jodi. We would play hide-and-seek, make him figure out which hand had the biscuit, or hide a biscuit in a pile of blankets. Or we would tell him get the ________", birdie, hammyster, kittycat, ect and he would run through the house to each room where the animal lived or stare outside at the fence for the cat or squirrel.
  • N

    Eating behaviors..

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    N
    Hello, I just wanted to send a quick update on Nulla. She is doing so well! We started a dog training course where my boyfriend and I are the alpha dogs. There is not treats involved and it has shown amazing results. Nulla has been in the course for about a month now. We have had no eating problems from her (no barfing, no not eating what we set our for her), no behavioral problems (no chewing my shoes, etc). She seems so happy and I am sure she is gaining weight (although I have not weighed her). I think dog training is completely necessary and we've seen HUGE results in Nulla. Everything I posted about before is no longer a concern. Thanks for all the input though. Take Care :)
  • wizardW

    Anxiety help

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    renaultf1R
    @sharronhurlbut: Re car rides, this is going to sound odd, but it does work for me and my 2 dogs. Even if you have walked your dogs before a car trip, I find the excitement of the "get into the car" and going makes there guts act up. So, here is what we do. We take the dogs a lot on vacation when we go by car. We walk the dogs in the am, feed and water. Get them into the car. Drive about 2 miles and stop and let them out to walk. Both always pee and poo when we stop. Once back in the car, they settle and are quiet. About a hr or so into the ride, they start to get "ACTIVE" again…we stop at a rest area, they go, and then they sleep the rest of the way. Could be the excitement of leaving home, the motion of the car or whatever, but these stops, even tho you want to get going...make the trip much easier on all involved. Give it a try. All you can lose is a bit of time... Sharron…I've had friends use that method as well...so I think you (and them) are on to something. Wizard...It is a tough road, separation anxiety. I never had much success with the DAP - spray or plug-in...and I used both for about half a year. I finally gave up on it. Although, my vet and the pet store I bought it at said they knew of people that had had success with it. Good for you for working with a behaviorist...they definitely will have better ideas about things to try. The second beastie was the golden ticket for Ruby though...and seriously, I've found that 2 b's are so much easier than one. So much so that I'm thinking of adding another either this year or next...and for that I might need my head examined.
  • U

    Help!

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    U
    Thanks guys! I will be checking those books out!