Skip to content

Major behavior change after 10 years!! Help!

Behavioral Issues
  • @rocky1 ...as i
    I wrote in 2016...I am sorry about your dog, but it's rare. Other drugs may be more dangerous and far less researched.

    DebraDownSouth Aug 28, 2016, 11:18 PM reply quote
    Rocky1, I am sorry about your dog, and absolutely liver is a KNOWN side effect, albeit small, with the drug. So anyone doubting you needs to do some research.

    However, your other information is a not accurate.

    first, no, clomicalm is not the doggy form of prozac.

    Second, 5-htp has toxicity also. Almost no drug comes without risks. http://www.ncbi.nlm.nih.gov/pubmed/10863592
    Add to the fact that prozac has been used and researched heavily, whereas research on 5-HTP is scarce in humans and almost nonexistent in dogs beyond the toxicity above. "natural" doesn't mean safe.
    http://psychology.wikia.com/wiki/Hydroxytryptophan_(5-)

    In humans it also can cause liver damage

    Tryptophan use has been associated with the development of serious conditions, such as liver and brain toxicity, and with eosinophilic myalgia syndrome (EMS), a potentially fatal disorder that affects the skin, blood, muscles, and organs (see "Overview" section). Such reports prompted the FDA to ban the sale of all tryptophan supplements in 1989. As with tryptophan, EMS has been reported in 10 people taking 5-HTP.
    Side effects of 5-HTP are generally mild and may include nausea, heartburn, gas, feelings of fullness, and rumbling sensations in some people. At high doses, serotonin syndrome, a dangerous condition caused by too much serotonin in the body, could develop. Talk to your health care provider before taking higher-than-recommended doses.
    People with high blood pressure or diabetes should talk to their doctor before taking 5-HTP.
    If you take antidepressants, you should not take 5-HTP (see "Possible Interactions" section).
    People with liver disease, pregnant women, and women who are breastfeeding should not take 5-HTP.<<

    Clomicalm (clomipramine hydrochloride) is a tricyclic antidepressant and affects chemicals in the brain (serotonin)
    Prozac, fluoxetine, is a selective serotonin reuptake inhibitor (SSRI) antidepressant drug . Its FDA-approved veterinary formulation is known as Reconcile.

    Clomicalm slows the reabsorption rate of the neurotransmitters serotonin and norepinephrine, allowing their levels to rise in the brain. This drug is mainly used to treat separation anxiety. Prozac, on the other hand, works by strongly blocking the reabsorption of serotonin allowing more serotonin to be available for extended periods of time.
    http://www.ehow.com/info_12227764_difference-between-clomicalm-prozac-dogs.html

    http://www.ncbi.nlm.nih.gov/pubmed/10863592

    Prozac, clomicalm and 5-HTP can all cause liver issues.

    Debra<<<<<

  • @rocky1 I'm so very sorry for your loss. They become such a part of our souls. I've already had a few tears over just the thought of what it will be like without him.

Suggested Topics

  • Help!

    Behavioral Issues
    17
    0 Votes
    17 Posts
    5k Views
    KipawaK
    Kipawa went through a rambunctious stage at 13 months - he didn't do anything bad, but he seemed to be 'testing' who the boss was. He was reminded, consistently. (Grin) At 15 months he started to show very nice maturation qualities and a complete understanding of his place in our family pack. Be patient, be consistent, give him lots of exercise and really praise him when he is good.
  • 0 Votes
    32 Posts
    17k Views
    Buddys PalB
    Wow! this is one of many, many threads that I have responded to and I am very interested in the outcome of Poopydog and the nipping. As I was going through the Thread, I really had to bypass any of the responses of those who enjoy attacking one another. I sure hope this behavior did not thwart our member who really needed help. The majority are replies to one another trying to impart important knowledge or experience to someone who did not ask for it in the first place. Don't try to sound important. Everyone is, just give happy good-hearted advice and let us just not dig into the other who has a different opinion. Just dig, digs, and more digs. Really getting old….........................I know you won't miss me, but this is just too much.................................................................
  • Please Help!!!!!!

    Behavioral Issues
    11
    0 Votes
    11 Posts
    4k Views
    S
    Fran, my older b and I are also those who can't sleep throught the night. So, we all get up and take care of business. At least your pup will out grow this… Any chance we will see you at the EBC specality in Aug in Auburn Wa again? I would love it!
  • Where do I begin… (HELP!)

    Behavioral Issues
    45
    0 Votes
    45 Posts
    18k Views
    phoenix3P
    Opps didnt know this topic had 5 pages i properly said something that was already mentioned lol :D
  • Strange behavior!!!

    Behavioral Issues
    11
    0 Votes
    11 Posts
    5k Views
    P
    I think you should go back to your vets especially as this has been happenig ever since the emergency surgery. It could just be coincidence I suppose, but if she were mine I'd want to check. As Pat says more information is needed before suggestions can be given.
  • Help with aggression

    Behavioral Issues
    8
    0 Votes
    8 Posts
    5k Views
    L
    Some basenjis seem to have particular kinds of dogs they don't like. My Abbey is best friends with a rottweiller, a black lab, and a dalmation, but she hates golden retrievers! What do they go by, coat color?? She goes after anything that moves at the vet's though. My first basenji many years ago, Pumpkin, climbed trees to get after squirrels, and fences were no problem either.