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Major behavior change after 10 years!! Help!

Behavioral Issues
  • DebraDownSouthD

    @rocky1 ...as i
    I wrote in 2016...I am sorry about your dog, but it's rare. Other drugs may be more dangerous and far less researched.

    DebraDownSouth Aug 28, 2016, 11:18 PM reply quote
    Rocky1, I am sorry about your dog, and absolutely liver is a KNOWN side effect, albeit small, with the drug. So anyone doubting you needs to do some research.

    However, your other information is a not accurate.

    first, no, clomicalm is not the doggy form of prozac.

    Second, 5-htp has toxicity also. Almost no drug comes without risks. http://www.ncbi.nlm.nih.gov/pubmed/10863592
    Add to the fact that prozac has been used and researched heavily, whereas research on 5-HTP is scarce in humans and almost nonexistent in dogs beyond the toxicity above. "natural" doesn't mean safe.
    http://psychology.wikia.com/wiki/Hydroxytryptophan_(5-)

    In humans it also can cause liver damage

    Tryptophan use has been associated with the development of serious conditions, such as liver and brain toxicity, and with eosinophilic myalgia syndrome (EMS), a potentially fatal disorder that affects the skin, blood, muscles, and organs (see "Overview" section). Such reports prompted the FDA to ban the sale of all tryptophan supplements in 1989. As with tryptophan, EMS has been reported in 10 people taking 5-HTP.
    Side effects of 5-HTP are generally mild and may include nausea, heartburn, gas, feelings of fullness, and rumbling sensations in some people. At high doses, serotonin syndrome, a dangerous condition caused by too much serotonin in the body, could develop. Talk to your health care provider before taking higher-than-recommended doses.
    People with high blood pressure or diabetes should talk to their doctor before taking 5-HTP.
    If you take antidepressants, you should not take 5-HTP (see "Possible Interactions" section).
    People with liver disease, pregnant women, and women who are breastfeeding should not take 5-HTP.<<

    Clomicalm (clomipramine hydrochloride) is a tricyclic antidepressant and affects chemicals in the brain (serotonin)
    Prozac, fluoxetine, is a selective serotonin reuptake inhibitor (SSRI) antidepressant drug . Its FDA-approved veterinary formulation is known as Reconcile.

    Clomicalm slows the reabsorption rate of the neurotransmitters serotonin and norepinephrine, allowing their levels to rise in the brain. This drug is mainly used to treat separation anxiety. Prozac, on the other hand, works by strongly blocking the reabsorption of serotonin allowing more serotonin to be available for extended periods of time.
    http://www.ehow.com/info_12227764_difference-between-clomicalm-prozac-dogs.html

    http://www.ncbi.nlm.nih.gov/pubmed/10863592

    Prozac, clomicalm and 5-HTP can all cause liver issues.

    Debra<<<<<

    Debra

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  • J

    @rocky1 I'm so very sorry for your loss. They become such a part of our souls. I've already had a few tears over just the thought of what it will be like without him.

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    KipawaK
    @DebraDownSouth: Fran, there are times when I might mean to be condescending, but I assure you that it won't be "a little" or usually any question. That you could take my comment above as condescending… I can only suggest you may simply want to block my posts because it is entirely unlikely I will write 100 words to say what I said in under 20 because SOMEONE might see my observation as insulting. Now if I had said it condescending, such as: How could you THINK it could be that? Don't you think any dog living with females would already have reacted? How silly! The person threw out the idea of periods, which sometimes could be it .. and btw, pregnancy hormones set some dogs off… but it hit me he had lived with them too long for that to be probably. It wasn't an insult to the OP, just a response. People contradict my ideas daily on here, doesn't make them condescending or insulting. THEN, I could see it. I simply tossed out a quick response addressing that logically it probably wasn't that. If you read that as condescending instead of my own view, I am sorry. One helpful rule for forums is that you look at any post and see if there is another TONE than the one you ascribed. If there is, take the other. Like your post. I COULD think you are a jerk, not at all "friendly," addressing this here and hijacking the thread instead of sending me a private message. Instead, because I see you post a lot and like you :), I took it exactly at face value... you simply are expressing your view and trying to be helpful. So please remove any tones you might ascribe to the answer. The tone in my head is simply factual, that I am not responsible for your taking that as condescending and probably won't be able to stop you seeing other posts that way. Now if I actually say something you cannot take any way than as an insult, feel free to let me know. But the above... sorry, Fran, it was simply a logical observation. LOL, and in fact, let me now be "condescending" to my post. (I am joking while making a point.) SOMEONE (but it will be me, since it just hit me where I could easily be wrong...) could have responded to my post and said: Yeah, but dds, you are wrong because maybe she has an infection or urinary tract infection also with a period, that might do it. See? Debra, not a problem. Thank you.
  • J

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  • A

    Major issues

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    When I first acquired my previous basenji the breeder suggested putting paper towels in the bottom of the crate (she can tear them up to her hearts content and even if she eats some if shouldn't cause problems) and to give frozen marrow bones to keep her occupied. There are also lots of interactive toys available that also keep her occupied.
  • N

    Eating behaviors..

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