Just thought I'd share an update on this.
I removed the blankets from the crate and replaced them with a mattress. We have been strict about her only staying in the crate at night. When we have had accidents I have cleaned up, with a dog urine killing spray, and placed her back in the crate.
Everything is progressing smoothly, not had any accidents for over a week now. So it's been a rather quick turnaround, lovely to have her properly crate trained again.
Thank you all for sharing advice on the situation.