training it (potty train, learning commands such as sit, no etc or remembering their names)
-from my experience it i harder to tach them so you really need to practice them few time in a day.
Removing it from its litter? Will it have separation anxiety?
-yes they would. 1st month would be difficult but after that they will feel more relaxed.
Will they be comfortable settling in a new home?
-it would take obviously but just be patient and always notice them for them to easily love you!